Liver Injury Associated With Ezetimibe Monotherapy
نویسندگان
چکیده
منابع مشابه
Cost-effectiveness of statin monotherapy and combination therapy with ezetimibe.
Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Several statin monotherapies and combination therapies of statin with ezetim...
متن کاملThe effects of statin monotherapy and low-dose statin/ezetimibe on lipoprotein-associated phospholipase A₂.
BACKGROUND Many of the pleiotropic effects of statins remain to be elucidated. HYPOTHESIS Different statin regimens with similar lipid-lowering efficacy may have different effects on biomarkers of atherothrombosis including lipoprotein-associated phospholipase A₂ (Lp-PLA₂ ). METHODS After a 4-week dietary lead-in, 82 hypercholesterolemic patients were randomized to 1 of 2 treatment groups: ...
متن کاملEfficacy of ezetimibe as monotherapy or combination therapy in hypercholesterolemic patients with and without diabetes.
Ezetimibe selectively inhibits dietary and biliary cholesterol absorption and reduces serum cholesterol levels when administered alone (monotherapy) and along with common lipid-regulating agents (combination therapy). To evaluate the effect of ezetimibe therapy on the lipid profile, glucose metabolism, and levels of cholesterol absorption and synthesis markers, we administered 10 mg ezetimibe t...
متن کاملEfficacy and safety of ezetimibe monotherapy in children with heterozygous familial or nonfamilial hypercholesterolemia.
OBJECTIVES To evaluate the lipid-altering efficacy and safety of ezetimibe monotherapy in young children with heterozygous familial hypercholesterolemia (HeFH) or nonfamilial hypercholesterolemia (nonFH). STUDY DESIGN One hundred thirty-eight children 6-10 years of age with diagnosed HeFH or clinically important nonFH (low-density lipoprotein cholesterol [LDL-C] ≥ 160 mg/dL [4.1 mmol/L]) were...
متن کاملDrug-Induced Liver Injury Associated with Complementary and Alternative Medicines
A 24-year-old man was admitted due to acute hepatitis with unknown etiology. After his condition and laboratory data gradually improved with conservative therapy, he was discharged 1 month later. Two months after his discharge, however, liver dysfunction reappeared. After his mother accidentally revealed that he took complementary and alternative medicine, discontinuation of the therapy caused ...
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ژورنال
عنوان ژورنال: CJC Open
سال: 2021
ISSN: 2589-790X
DOI: 10.1016/j.cjco.2020.09.018